Our highly sensitive, proven FAIMS technology and state-of-the art laboratories produce an information-rich chemical spectrum, detecting concentrations of volatile chemicals with part per billion or even part per trillion levels of sensitivity.

Chemical analysis of breath and other biospecimens including urine, blood and serum

Our FAIMS technology detects concentrations of volatile chemical markers with up to part per trillion sensitivity and precision.

Our experienced analytical chemistry team analyzes each sample through our state-of-the-art laboratories including our proven Field Asymmetric Ion Mobility Spectrometer (FAIMS) technology. FAIMS uses an asymmetric alternating voltage to separate volatile chemicals by size and mobility, allowing us to selectively and reproducibly probe for discrete populations of volatile chemicals in order to determine their concentration in the sample.

The appropriate FAIMS platform is selected depending on the sample type being analyzed (read more about the Lonestar VOC Analyzer and ultraFAIMS).

Breath Biopsy® Complete Guide - VOCs as Biomarkers for Disease


Full discovery or targeted analysis

Our FAIMS technology provides a complete analysis of all volatile organic compounds (VOCs) present in the sample, ideal for biomarker discovery. Once the candidate biomarkers have been identified, the same FAIMS technology can be used to perform a targeted analysis of a specific subset of volatile markers for validation purposes.

Quality control and data security

Our quality management system (QMS) includes standard operating procedures covering all activities.

Rigorous quality control checks throughout sample analysis ensure the integrity of the result and protect against contamination or systematic errors. We perform a number of daily and weekly QC checks to monitor a range of instrument parameters, and use blanks and standard compounds to monitor background, sensitivity, limit of detection and signal-to-noise ratio.

The analyzed chemical spectra are combined with sampler data logs and other clinical metadata into a secure, searchable, cloud-hosted data repository. 

FAIMS technology shows excellent reproducibility. Standard compounds were loaded onto sorbent tubes at a defined amount and analyzed using GC-FAIMS (Lonestar VOC Analyzer). The experiment was repeated regularly to assess the variation over time. Data for two compounds over a three month period is shown. The relative standard deviation is 6.1 % for methyl salicylate and 3.4 % for D-limonene. 

Working in Owlstone medical lab

Get in touch with the Owlstone team for further information and pricing

request pricing