3.0 Breath Biopsy Target VOC Kit

Targeted analysis of specific VOCs of interest using our Breath Biopsy Services

  • Collect reliable breath samples and send to Owlstone Medical for analysis
  • Conditioned and QC checked Breath Biopsy Cartridge and Mask
  • Standard data analysis and reporting
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Overview

Quantitative Analysis of Target VOCs in Breath

The 3.0 Breath Biopsy Target VOC Kits provide a quantitative analysis of specific VOCs of interest, ideal for validation of biomarkers that have already been identified in previous studies. The Target VOC Kits include the consumables required for collection of high-quality breath samples using the ReCIVA Breath Sampler. Each kit contains a Breath Biopsy Cartridge to collect, stabilize and pre-concentrate the VOCs, enhancing the sensitivity of detection, and a disposable Breath Biopsy Mask.

All of the consumables are sealed, ready to use, and are manufactured and quality checked to the exacting standards required for the analysis of VOC biomarkers in breath, ensuring that the samples you collect are of the highest quality throughout your study.

Breath Biopsy Cartridges containing VOCs are returned to Owlstone Medical after use, using the pre-paid return envelope provided, and the target VOCs are analyzed in the Breath Biopsy Services laboratory using our Breath Biopsy analytical platform including GC-MS or GC-FAIMS. 


“The ability to run targeted analysis of specific VOCs of interest and to have access to large patient populations via the Breath Biopsy digital biobank will enable us to greatly speed up the process of validating the VOC biomarkers we have identified in our previous studies.” Professor Chris Mayhew, Director of the Institute for Breath Research at the University of Innsbruck

Breath Biopsy 3.0 Target VOC Services Example Report

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Breath Biopsy Cartridges

Cartridge Conditioning & QC

Each Breath Biopsy Cartridge contains two pairs of VOC sample tubes prepared using our proprietary conditioning and QC process which includes optimized parameters designed to remove even low levels of contaminants that could interfere with detection of VOCs in breath, and enable enhanced sensitivity for breath analysis methods running in splitless mode. 

  • Thermal conditioning at > 300 °C for 4 hours.
  • QC process includes analysis of blank Breath Biopsy Cartridges by TD-GC-MS, and evaluation of spectra against our database of blank profiles to ensure any background is below a total VOC count of 50 ng on trap mass threshold.
  • Capped before and after breath collection to minimize contamination from external VOCs.

Breath Biopsy Masks

Mask Conditioning & QC

Breath Biopsy Masks are manufactured to the specific requirements for breath VOC analysis.

  • Initial conditioning bake 200 °C for 8 hours.
  • Clean and wash process using acid/detergent mix, followed by rinse/dry at elevated temperature.
  • Secondary bake at 200 °C for 680 hours.
  • Integral filter is baked for 16 hours at 75 °C prior to assembly.
  • QC includes mock breath collection (global analysis of VOCs by GC-MS).
  • Vacuum sealed individually, ready to use.

How to Analyze

Targeted VOC Analysis Service

Once the breath samples have been collected using the ReCIVA Breath Sampler and Breath Biopsy Kit, the Breath Biopsy Cartridges are returned to Owlstone Medical's Breath Biopsy Services Laboratory for analysis, using the pre-paid envelope provided.

Our team of expert analytical chemists perform a quantitative analysis of the specific VOCs of interest your samples using our Breath Biopsy analytical platform including GC-MS or GC-FAIMS.

Once your study is complete, our experts review the results with you. We provide a detailed report, containing all the analysis of your Breath Biopsy samples.

Breath Biopsy® Complete Guide - VOCs as Biomarkers for Disease

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What's inside the box

3.0 Breath Biopsy Target VOC Kit includes:

  • One Breath Biopsy Cartridge
    Four conditioned VOC sample tubes
    QC checked
    Capped and ready to use
  • One disposable Breath Biopsy Mask
    Conditioned
    Integral filter
    QC checked
    Vacuum sealed and ready to use
  • Encrypted USB drive
    For transfer of patient metadata
  • Return envelope
    Breath Biopsy Cartridges are returned to Owlstone Medical for analysis
  • Breath Target VOC Service
    Performed in Owlstone Medical's Breath Biopsy Services Laboratory using the Breath Biopsy analytical platform including GC-MS or GC-FAIMS
    Standard data analysis and reporting
    Custom data analysis available (additional fees apply)

Get in touch with our team today for additional information and pricing

Request pricing

Get in touch with our team today for 3.0 Breath Biopsy Target VOC Kit further information and pricing

Request pricing