Arafat Mahmood at the Breath Biopsy Conference 2021

Early Career presentation - Metal oxide based chemiresistive sensors for detecting and management of diabetes from exhaled breath (20min)

 

The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference:

Express Interest

Talk Abstract:

Diabetes is a chronic health problem worldwide and the increased incidence among adults and adolescents is a growing public health concern. The elevated level of blood glucose in diabetes results in serious medical complications and life-threatening side effects. The invasive procedures in combination with inconveniences, ambiguity in interpretations, and cost make patients reluctant to monitor diabetes regularly. In clinical settings, researchers have investigated the presence of acetone, ethanol, methanol, propane, methyl nitrate, 2-pentyl nitrate, isoprene, ethyl benzene, xylene, carbon monoxide, and carbon dioxide in diabetic breath using sophisticated spectroscopic systems, such as proton transfer reaction time-of-flight mass spectrometry, gas chromatography and mass spectroscopy. Results revealed that the concentration of acetone, isoprene, methyl nitrate and carbon monoxide is elevated up to 10 folds in diabetic breath. However, the concentration of the biomarkers is in the range of parts per million (ppm) to parts per trillion (ppt) levels. Non-invasive, miniaturized and portable chemiresistive gas sensors based on metal oxides, such as SnO2, ZnO, TiO2, In2O3 and WO3 are capable of detecting breath biomarkers at very low concentrations in exhaled breath. The detection capabilities of chemiresistive sensors can be further improved by increasing the active surface area, by using heterostructures/heterojunctions, by loading catalytic nanoparticles on the surface and/or by adding appropriate dopants in metal oxide matrix. This review study will provide the background information, standardized methodology and our approach is expected to facilitate the detection and management of diabetes using metal oxide based chemiresistive sensors.

 

Speaker Biography:

Dr. Md. Arafat Mahmood (M. M. Arafat) is currently working as a Marie Curie Research Fellow at the Department of Mechanical Engineering and Aeronautics, City University of London, UK. He was awarded the “Sensor4Diabetes” project (898736) from European Commission under the Marie Skłodowska-Curie Individual Fellowships. He is working on gas sensor technology for detecting diabetes from exhaled breath.  Arafat obtained his Ph.D. degree from University of Malaya, on gas sensors technology using metal oxide nanostructures. He received his M.Sc. degree from the same university on microelectronic packaging materials. He completed his Bachelor degree at the Department of Materials and Metallurgical Engineering, BUET, Bangladesh.

Dr. Arafat is an expert in the field of nano-materials synthesis, nano-composite materials, materials characterizations, gas sensors, soldering materials etc. He developed novel nanostructured materials for various applications by simple, robust, and highly scalable techniques. Arafat has published a number of articles in recognized peer reviewed journals. He has presented articles at international conferences worldwide. He also worked as Review Editor in Reference Module in Materials Science and Materials Engineering. Currently, he is the reviewer of various reputed journals.

The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference:

Express Interest