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Respiratory Diseases

Breath biomarker discovery with Breath Biopsy® could lead to non-invasive precision medicine and exacerbation detection for asthma, COPD and other chronic airway diseases

Biomarkers for Respiratory Disease

Biomarkers for Respiratory Disease

Chronic inflammatory airway disease, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF) affect over 500M people worldwide.1 These conditions are highly heterogeneous but share common clinical presentations, this makes accurate diagnosis and effective treatment a critical challenge.

Human breath contains over 1,000 different volatile organic compounds (VOCs) which can originate from endogenous metabolism or exogenous sources such as diet, the environment or the microbiome. Collecting and analyzing these compounds can be a rich source of information relevant to health and disease. By developing Breath Biopsy, Owlstone Medical have become the world-leaders in robust and reliable, non-invasive breath collection for biomarker discovery research.

1. Labaki, W.W., Han, M.K., Chronic respiratory diseases: a global view Lancet Resp Med 8 (6), 531-533 (2020)

About Breath Biomarkers


Biomarkers on breath are well suited to the study, diagnosis and treatment of respiratory diseases. They can originate directly within diseased airways or can be transferred into breath from the bloodstream. As such breath tests have the potential to detect local and systemic markers of respiratory diseases. Breath Biopsy uses the ReCIVA® Breath Sampler for non-invasive breath sample collection and provides robust global biomarker analysis pipelines using GC-MS analysis provided through Breath Biopsy OMNI. Our analysis and reporting capabilities allow us to provide specialized feedback that can include compounds with existing reported links to respiratory diseases of interest.


We’re working on respiratory diseases with these groups:

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Our team organize and attend a range of events to showcase Breath Biopsy. This includes our webinar series and the annual Breath Biopsy Conference (BBCon), a keystone event for the breath research community.

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Catch-up on recent breath research with on-demand presentations from the Breath Biopsy Conference

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Speakers from the Breath Biopsy Conference 2021

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