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Cancer

Non-invasive biomarker discovery with Breath Biopsy® could help to enable early detection of cancer by measuring volatile organic compounds in patients' breath

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Poster
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Poster: European Association for Cancer Research

Targeting tumour-associated aldo-keto reductase activity with exogenous volatile organic compound (EVOC) Probes to detect lung cancer with Mariana Leal

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Angie Tjandra at BBCon22
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Presentation: Angie Tjandra at BBCon22

Developing colorimetric sensors for early cancer detection from breath

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Blog
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Article: Exhaled Breath Biopsy - a new cancer detection paradigm

Read this article on Breath Biopsy and cancer detection by Balkees Abderrahman from the University of Texas

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Poster
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Poster Presentation: Early Detection of Cancer Conference

Breath-based detection of lung cancer using EVOC targeting β-glucuronidase in the tumour microenvironment

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One in two people will get cancer in their lifetimes. Globally, lung cancer is the most common cancer in the world with 2.1 million new cases identified in 2018. ln the early stages, the chance of surviving cancer is ten times higher and the cost of treatment ten times lower than in the later stages, and so detecting cancer early is by far the best way to improve cancer survival.

The Breath Biopsy Lung Cancer Screening Test in development involves a combination of VOCs associated with lung cancer from an early stage, and an EVOC Probe administered from outside the body to target specific cancer pathways. Both sets of biomarkers can be detected non-invasively though Breath Biopsy and work is underway to integrate them into a single cancer detection analysis. Our work suggests that almost 90% of Stage I lung cancers can be targeted, with the potential to have a transformative effect on cancer detection.

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Further Reading

Other recommended reading:

Respiratory infographic

Owlstone Medical 2.0 Breath Biopsy Kit box - view from top

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