Morad Nakhleh at the Breath Biopsy Conference 2021

Sampling and Analysis session - Towards standardization: Breath Biopsy® OMNI Assay for enhanced biomarker discovery (40min)

 

The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference:

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Talk Abstract:

Exhaled Volatile Organic Compounds (VOCs) hold the potential to be effective noninvasive biomarkers for diagnostics and precision medicine. The success of biomarker discovery studies in the field heavily relies on optimized sample acquisition and analysis. That includes, but is not limited to, maximizing the number of biologically relevant compounds detectable by the analytical platform, and reducing process variability.

Developing a fit for purpose end-to-end breath sampling and analysis platform remains a significant challenge, particularly due to the complex nature of the breath matrix and external sources of VOCs contaminating the samples.

This presentation aims to provide data-driven insights, gained through the development of the OMNI Assay, towards enhancement of global biomarker discovery capabilities and data quality. We will focus on the optimization of approaches for sample acquisition, analysis and quality control.

Finally, we will share and recommend standardized key metrics, that not only allow decision making and monitoring of the platform’s performance, but also have the potential to drive the future of standardized scientific reporting and communication within the breath analysis community.

Speaker Biography:
Morad K. Nakhleh Joined Owlstone Medical in 2018, in his role as Lead Biomarker Discovery Scientist he leads the scientific and technical development of the biomarker discovery platforms and solutions for exhaled VOCs sampling and analysis. Morad has more than 11 years of experience in biomarker discovery and exhaled breath analysis. He holds a degree in Emergency medicine, Master’s degree in medical sciences and PhD in Nano-biotechnology. Prior to joining Owlstone, as part of his post-doctoral research, Morad focused on understanding the origins and biochemistry of VOCs, mainly in respiratory diseases.

The Breath Biopsy Conference 2022 is scheduled for 1st-3rd November. Click the button to express interest in the next Breath Biopsy Conference:

Express Interest