Panel Discussion at the 2020 Breath Biopsy Conference
Discussion (1 hour) - Why is it important for breath research to understand the biological origins of VOCs?
Have your say. Tell us what you think about this topic on the Breath Biopsy Community.
Chair:
Billy Boyle, Owlstone Medical
Panellists:
Marc van der Schee, Owlstone Medical
Pierre-Hugues Stefanuto, University of Liege
Terence Risby, Johns Hopkins Bloomberg School of Public Health
Rianne Fijten, Maastricht University
0:00 Welcome to the Breath Biopsy Conference Panel Discussion
0:20 Introduction from Billy Boyle
2:20 Panelists Introduction
4:05 How well do we currently understand the biological origins of VOCs?
14:46 Do you think we should focus on understanding a particular pathway using specific probes, or should we do more discovery-base studies?
23:05 To what extent should we use in-vitro and ex-vivo data to identify and confirm the origins of VOCs in breath?
29:42 How do other sample types (blood, urine, etc) play a role in understanding VOCs and their biological origin?
35:00 To what extent are VOCs related to microbiome? Do you view these as exogenous or endogenous? What are their potential applications?
40:14 Several VOCs have signaling roles in biology, do you think there could be others? Do you think VOCs could be deployed as a therapeutic?
44:57 Would the study of metabolic disorders help understand specific VOC pathways in-vivo?
47:52 How best to use analytical/sensor tools (spectrometry, e-nose) and at what point should you start thinking about using these tools within breath research?
56:00 What are the top tips the breath field can copy or adapt from adjacent fields?
1:01:46 Closing remarks from Billy Boyle
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