As the majority of researchers in the breath analysis field can tell you, breath research is not new. Modern breath testing began in 1971 with the Nobel Prize winner Linus Pauling. However, with the development of new technologies in recent years there has been an upsurge in the number of publications that include breath analysis. This can be shown through simple searches on the Pubmed database (see figure 1).
Owlstone Medical are leading the way in breath analysis with the development of the Breath Biopsy platform. Improvements to the collection, storage and analysis of breath samples that have transformed the way in which breath can be utilized in clinical research, enabling breath analysis to be included in large scale clinical trials.
Breath is a valuable source of potential biomarkers for a wide range of diseases, and it has the benefit of being completely non-invasive, which is a game-changer for the diagnostics market, as well as opening the door to many other potential applications.
Number of Publications involving breath research per calendar year (1990-2018)
Breath research applications are continuing to rise. As figure 2 shows, there are a few research categories that show focus areas of breath researchers; namely Helicobater pylori which has an established breath test using 13C Urea. However, techniques and technology advances other applications in cancer and metabolic conditions are growing.
The expansion of new application areas for breath research is indicative of the desire for a non-invasive test to improve patient acceptance and experience different diagnostic areas. Thereby increasing the chances of detecting diseases and health conditions early, to enable more effective treatment.
The Cumulative number of publications by research category from 1993 to 2018
If you want to learn more about how Owlstone Medical's Breath Sampling and Analysis technology and Services are being utilized in early detection and precision medicine, why not download our free ebook: Breath Biopsy: The Complete Guide?