This blog was initially published in December 2018. We aim to update the content on a regular basis. The last update was on 20th January 2020.


Cumulative number of clinical trials involving breath analysis

Analysis of all clinical trial data1 shows that between 1994 and 2019, 706 trials have used or are using a form of breath analysis in their workflow. During this time period there has been a consistent rise in the number of clinical trials involving breath analysis starting each year. This trend indicates a growing interest in the clinical application of breath-based biomarkers (Figure 1).

Clinical Trials blog updated graph
Figure 1. There has been a steady rise in numbers of clinical trials using breath analysis.

Study area categorization in 706 clinical trials using breath analysis

The identified clinical trials cover a range of conditions and utilities, demonstrating the breadth of applications where breath analysis is thought to be useful. A breakdown of the study areas categories of the represented in these trials is shown in Figure 2. 

Clinical trials data - Bubble % v3-01
Figure 2. Breakdown of study area category of 706 clinical trials using breath analysis in their workflow. Trials analysing a specific methodology or tool for disease detection/type/severity were classified as ‘Test Development’. Studies that use breath research in theare analysis or comparison of therapies or treatments were considered to be ‘Drug Development’ trials. All other trials were classified by disease area. A significant proportion of the Gastrointestinal studies focus on H. Pylori infections. 

Download the list of clinical trials involving breath analysis as an excel spreadsheet:


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1. Data from

ReCIVA Breath Sampler device

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