This blog was initially published in December 2018. We aim to update it with new data on a regular basis. The last update was on 1st June 2022.
Cumulative number of clinical trials involving breath analysis
Analysis of all clinical trial data1 shows that between 1994 and 2021, 846 trials have used or are using a form of breath analysis in their workflow. During this time period there has been a consistent rise in the number of clinical trials involving breath analysis starting each year. This trend indicates a growing interest in the clinical application of breath-based biomarkers (Figure 1). We had expected to see a decrease in the number of clinical trials launching in 2020 and 2021, as a consequence of the COVID-19 pandemic. However, the projected decrease in some traditionally popular areas of breath research has seemingly been counterbalanced by the large increase in clincal trials relating to infectious diseases (and COVID-19 in particular) - with numbers remaining strong (over 70 new trials started each year from 2019-21).
Study area categorization in 846 clinical trials using breath analysis
The identified clinical trials cover a range of conditions and utilities, demonstrating the breadth of possible applications for breath analysis. A breakdown of the research areas represented in these trials is shown in Figure 2.
If you’re looking for help planning your own breath research studies, you can read our articles on study design or get in touch to talk to talk to one of our in-house experts.
If you want to learn more about how Owlstone Medical®'s Breath Sampling and Analysis technology and Services are being utilized in early detection and precision medicine, why not download our free ebook: Breath Biopsy: The Complete Guide?
1. Data from https://clinicaltrials.gov/.