Liver Graphic

Liver Diseases

Breath biomarker discovery with Breath Biopsy® could lead to non-invasive early detection and disease progression monitoring for NAFLD, NASH and other liver diseases.

Liver Disease

Biomarkers for Liver Disease

Today as many as 3 in 10 adults and 1 in 10 children are affected by liver disease in some countries.1 Despite increasing incidence, detecting liver disease, such as non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH) and more advanced cirrhosis, is challenging. These conditions all share common clinical presentations, making accurate diagnosis and effective treatment a critical challenge.

Human breath contains over 1,000 different volatile organic compounds (VOCs) which can originate from endogenous metabolism or exogenous sources such as diet, the environment or the microbiome. Collecting and analyzing these compounds can be a rich source of information relevant to health and disease. By developing Breath Biopsy®, Owlstone Medical have become the world-leaders in robust and reliable, non-invasive breath collection for biomarker discovery research.

1.Definition & Facts of NAFLD & NASH: 

About Breath Biomarkers

Biomarkers of liver disease originate directly within the liver and are then transferred into breath via the bloodstream. As such, breath tests have the potential to detect systemic markers of liver diseases. Breath Biopsy uses the ReCIVA® Breath Sampler for non-invasive breath sample collection and provides robust biomarker discovery pipelines using GC-MS analysis provided through Breath Biopsy Services.


We’re working on liver disease with these groups:

University of Birmingham logo Cancer Research UK Logo Cleveland Clinic News



Our team organize and attend a range of events to showcase Breath Biopsy. This includes our webinar series and the annual Breath Biopsy Conference (BBCon), a keystone event for the breath research community.

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Catch-up on recent breath research with on-demand presentations from the Breath Biopsy Conference

Watch on-demand
Speakers from the Breath Biopsy Conference 2021

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